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A live-cell, high-content imaging survey of 206 endogenous factors across five stress conditions reveals context-dependent survival effects in mouse primary beta cells
AIMS/HYPOTHESIS: Beta cell death is a hallmark of diabetes. It is not known whether specific cellular stresses associated with type 1 or type 2 diabetes require specific factors to protect pancreatic beta cells. No systematic comparison of endogenous soluble factors in the context of multiple pro-ap...
Autores principales: | Yang, Yu Hsuan Carol, Wills, Quin F., Johnson, James D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415993/ https://www.ncbi.nlm.nih.gov/pubmed/25773404 http://dx.doi.org/10.1007/s00125-015-3552-5 |
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