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Disulfiram Attenuates Osteoclast Differentiation In Vitro: A Potential Antiresorptive Agent

Disulfiram (DSF), a cysteine modifying compound, has long been clinically employed for the treatment of alcohol addiction. Mechanistically, DSF acts as a modulator of MAPK and NF-κB pathways signaling pathways. While these pathways are crucial for osteoclast (OC) differentiation, the potential influ...

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Detalles Bibliográficos
Autores principales:	Ying, Hua, Qin, An, Cheng, Tak S., Pavlos, Nathan J., Rea, Sarah, Dai, Kerong, Zheng, Ming H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416043/ https://www.ncbi.nlm.nih.gov/pubmed/25928135 http://dx.doi.org/10.1371/journal.pone.0125696

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