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Endothelial cells direct human mesenchymal stem cells for osteo- and chondro-lineage differentiation through endothelin-1 and AKT signaling

INTRODUCTION: Human mesenchymal stem cells (hMSCs) reside in a perivascular niche of the body, suggesting that they interact closely with vascular endothelial cells (ECs) through cell-cell interaction or paracrine signaling to maintain cell functions. Endothelin-1 (ET1) is a paracrine factor mainly...

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Detalles Bibliográficos
Autores principales:	Tsai, Tsung-Lin, Wang, Bowen, Squire, Matthew W, Guo, Lian-Wang, Li, Wan-Ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416238/ https://www.ncbi.nlm.nih.gov/pubmed/25998005 http://dx.doi.org/10.1186/s13287-015-0065-6

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