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Acthi, a thiazole biosynthesis enzyme, is essential for thiamine biosynthesis and CPC production in Acremonium chrysogenum

BACKGROUND: The filamentous fungus Acremonium chrysogenum is an important industrial fungus and is used in the production of the β-lactam antibiotic cephalosporin C. Little is known regarding the molecular and biological mechanisms of how this industrial strain was improved by mutagenesis and molecu...

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Detalles Bibliográficos
Autores principales:	Liu, Yan, Zhang, Wei, Xie, Liping, Liu, Hong, Gong, Guihua, Zhu, Baoquan, Hu, Youjia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416257/ https://www.ncbi.nlm.nih.gov/pubmed/25886533 http://dx.doi.org/10.1186/s12934-015-0235-3

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