Immunogenicity of idursulfase and clinical outcomes in very young patients (16 months to 7.5 years) with mucopolysaccharidosis II (Hunter syndrome)

BACKGROUND: Twenty-eight treatment-naïve mucopolysaccharidosis II patients (16 months–7.5 years) received 0.5 mg/kg idursulfase weekly for one year in NCT00607386. Serum anti-idursulfase immunoglobulin G antibodies (Abs) were seen in 68% of patients. METHODS: This post hoc analysis examined the rela...

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Detalles Bibliográficos
Autores principales: Pano, Arian, Barbier, Ann J, Bielefeld, Bonnie, Whiteman, David AH, Amato, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416269/
https://www.ncbi.nlm.nih.gov/pubmed/25902842
http://dx.doi.org/10.1186/s13023-015-0265-2

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