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Biosynthetic Versatility and Coordinated Action of 5′-Deoxyadenosyl Radicals in Deazaflavin Biosynthesis

[Image: see text] Coenzyme F(420) is a redox cofactor found in methanogens and in various actinobacteria. Despite the major biological importance of this cofactor, the biosynthesis of its deazaflavin core (8-hydroxy-5-deazaflavin, F(o)) is still poorly understood. F(o) synthase, the enzyme involved,...

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Detalles Bibliográficos
Autores principales: Philmus, Benjamin, Decamps, Laure, Berteau, Olivier, Begley, Tadhg P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416281/
https://www.ncbi.nlm.nih.gov/pubmed/25781338
http://dx.doi.org/10.1021/ja513287k

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