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Biosynthetic Versatility and Coordinated Action of 5′-Deoxyadenosyl Radicals in Deazaflavin Biosynthesis
[Image: see text] Coenzyme F(420) is a redox cofactor found in methanogens and in various actinobacteria. Despite the major biological importance of this cofactor, the biosynthesis of its deazaflavin core (8-hydroxy-5-deazaflavin, F(o)) is still poorly understood. F(o) synthase, the enzyme involved,...
Autores principales: | Philmus, Benjamin, Decamps, Laure, Berteau, Olivier, Begley, Tadhg P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2015
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416281/ https://www.ncbi.nlm.nih.gov/pubmed/25781338 http://dx.doi.org/10.1021/ja513287k |
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