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Accumulation of invariant NKT cells with increased IFN-γ production in persistent high-risk HPV-infected high-grade cervical intraepithelial neoplasia

BACKGROUND: Persistent high-risk human papillomavirus (HR-HPV) infection has been implicated in the development of high-grade cervical intraepithelial neoplasia (CIN) and cervical cancer. Invariant natural killer T (iNKT) cells produce large amounts of cytokines to regulate immune responses. However...

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Detalles Bibliográficos
Autores principales: Hu, Ting, Yang, Pei, Zhu, Hongmei, Chen, Xinlian, Xie, Xiaoyan, Yang, Mei, Liu, Shanling, Wang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416328/
https://www.ncbi.nlm.nih.gov/pubmed/25885042
http://dx.doi.org/10.1186/s13000-015-0254-8