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Concept and application of ideal protein for pigs

Knowledge about the amino acid requirements and the response of pigs to the amino acid supply is essential in feed formulation. A deficient AA supply results in a reduction in performance while an oversupply is costly and leads to excessive nitrogen excretion with a potentially negative environmenta...

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Autores principales: van Milgen, Jaap, Dourmad, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416387/
https://www.ncbi.nlm.nih.gov/pubmed/25937926
http://dx.doi.org/10.1186/s40104-015-0016-1
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author van Milgen, Jaap
Dourmad, Jean-Yves
author_facet van Milgen, Jaap
Dourmad, Jean-Yves
author_sort van Milgen, Jaap
collection PubMed
description Knowledge about the amino acid requirements and the response of pigs to the amino acid supply is essential in feed formulation. A deficient AA supply results in a reduction in performance while an oversupply is costly and leads to excessive nitrogen excretion with a potentially negative environmental impact. Amino acid requirements are determined to a large extent by the protein deposition in the body and, for lactating sows, by the protein exported in the milk. The concept of ideal protein was developed more than 50 years ago and refers to a protein with an amino acid profile that exactly meets the animal’s requirement so that all amino acids are equally limiting for performance. Because Lys typically is the first-limiting amino acid, the ideal amino acid profile is often expressed relative to Lys. Although the ideal protein profile is often assumed to be constant for a given production stage, (small) changes in the ideal protein profile can occur within a production stage. This can be caused by changes in the relative contribution of the different components of amino acid requirements during the productive life on the animal (e.g. changes in the relative contribution of growth and maintenance). Amino acids requirements can be determined experimentally using dose–response studies. The design of the study, the chosen response criterion, and the statistical model affect the requirement estimate. Although considerable experimental work has been carried out to determine the requirements for Lys, Met, Thr, and Trp in growing pigs (and to a lesser extent in sows), little is known about the requirements for the other essential amino acids. Experimental dose–response studies generally focus on the requirement and less on the overall response (i.e. what are the consequences of an amino acid deficiency?). This latter aspect is, to some extent, accounted for in modelling approaches that quantify the response of the animal to the amino acid supply in a dynamic way. The paper describes the origin of ideal protein and illustrates how fundamental concepts of amino acid nutrition have been integrated in practical modeling approaches for the nutrition of growing pigs and sows.
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spelling pubmed-44163872015-05-02 Concept and application of ideal protein for pigs van Milgen, Jaap Dourmad, Jean-Yves J Anim Sci Biotechnol Review Knowledge about the amino acid requirements and the response of pigs to the amino acid supply is essential in feed formulation. A deficient AA supply results in a reduction in performance while an oversupply is costly and leads to excessive nitrogen excretion with a potentially negative environmental impact. Amino acid requirements are determined to a large extent by the protein deposition in the body and, for lactating sows, by the protein exported in the milk. The concept of ideal protein was developed more than 50 years ago and refers to a protein with an amino acid profile that exactly meets the animal’s requirement so that all amino acids are equally limiting for performance. Because Lys typically is the first-limiting amino acid, the ideal amino acid profile is often expressed relative to Lys. Although the ideal protein profile is often assumed to be constant for a given production stage, (small) changes in the ideal protein profile can occur within a production stage. This can be caused by changes in the relative contribution of the different components of amino acid requirements during the productive life on the animal (e.g. changes in the relative contribution of growth and maintenance). Amino acids requirements can be determined experimentally using dose–response studies. The design of the study, the chosen response criterion, and the statistical model affect the requirement estimate. Although considerable experimental work has been carried out to determine the requirements for Lys, Met, Thr, and Trp in growing pigs (and to a lesser extent in sows), little is known about the requirements for the other essential amino acids. Experimental dose–response studies generally focus on the requirement and less on the overall response (i.e. what are the consequences of an amino acid deficiency?). This latter aspect is, to some extent, accounted for in modelling approaches that quantify the response of the animal to the amino acid supply in a dynamic way. The paper describes the origin of ideal protein and illustrates how fundamental concepts of amino acid nutrition have been integrated in practical modeling approaches for the nutrition of growing pigs and sows. BioMed Central 2015-04-11 /pmc/articles/PMC4416387/ /pubmed/25937926 http://dx.doi.org/10.1186/s40104-015-0016-1 Text en © van Milgen and Dourmad; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
van Milgen, Jaap
Dourmad, Jean-Yves
Concept and application of ideal protein for pigs
title Concept and application of ideal protein for pigs
title_full Concept and application of ideal protein for pigs
title_fullStr Concept and application of ideal protein for pigs
title_full_unstemmed Concept and application of ideal protein for pigs
title_short Concept and application of ideal protein for pigs
title_sort concept and application of ideal protein for pigs
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416387/
https://www.ncbi.nlm.nih.gov/pubmed/25937926
http://dx.doi.org/10.1186/s40104-015-0016-1
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