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Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer
TMPRSS2-ERG junction oncogene is present in more than 50% of patients with prostate cancer and its expression is frequently associated with poor prognosis. Our aim is to achieve gene knockdown by siRNA TMPRSS2-ERG and then to assess the biological consequences of this inhibition. First, we designed...
Autores principales: | Urbinati, Giorgia, Ali, Hafiz Muhammad, Rousseau, Quentin, Chapuis, Hubert, Desmaële, Didier, Couvreur, Patrick, Massaad-Massade, Liliane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416711/ https://www.ncbi.nlm.nih.gov/pubmed/25933120 http://dx.doi.org/10.1371/journal.pone.0125277 |
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