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Syk Tyrosine Kinase Is Critical for B Cell Antibody Responses and Memory B Cell Survival

Signals from the BCR are required for Ag-specific B cell recruitment into the immune response. Binding of Ag to the BCR induces phosphorylation of immune receptor tyrosine-based activation motifs in the cytoplasmic domains of the CD79a and CD79b signaling subunits, which subsequently bind and activa...

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Detalles Bibliográficos
Autores principales:	Ackermann, Jochen A., Nys, Josquin, Schweighoffer, Edina, McCleary, Scott, Smithers, Nicholas, Tybulewicz, Victor L. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2015
Materias:	Antigen Recognition and Responses
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416743/ https://www.ncbi.nlm.nih.gov/pubmed/25862820 http://dx.doi.org/10.4049/jimmunol.1500461

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