Cargando…
Acidosis Mediates the Switching of G(s)-PKA and G(i)-PKC(ε) Dependence in Prolonged Hyperalgesia Induced by Inflammation
Chronic inflammatory pain, when not effectively treated, is a costly health problem and has a harmful effect on all aspects of health-related quality of life. Previous studies suggested that in male Sprague Dawley rats, prostaglandin E(2) (PGE(2))-induced short-term hyperalgesia depends on protein k...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416776/ https://www.ncbi.nlm.nih.gov/pubmed/25933021 http://dx.doi.org/10.1371/journal.pone.0125022 |