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Predicting Human Genetic Interactions from Cancer Genome Evolution

Synthetic Lethal (SL) genetic interactions play a key role in various types of biological research, ranging from understanding genotype-phenotype relationships to identifying drug-targets against cancer. Despite recent advances in empirical measuring SL interactions in human cells, the human genetic...

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Detalles Bibliográficos
Autores principales:	Lu, Xiaowen, Megchelenbrink, Wout, Notebaart, Richard A., Huynen, Martijn A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416779/ https://www.ncbi.nlm.nih.gov/pubmed/25933428 http://dx.doi.org/10.1371/journal.pone.0125795

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