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Estimating the In Vivo Killing Efficacy of Cytotoxic T Lymphocytes across Different Peptide-MHC Complex Densities

Cytotoxic T lymphocytes (CTLs) are important agents in the control of intracellular pathogens, which specifically recognize and kill infected cells. Recently developed experimental methods allow the estimation of the CTL's efficacy in detecting and clearing infected host cells. One method, the...

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Detalles Bibliográficos
Autores principales: Garcia, Victor, Richter, Kirsten, Graw, Frederik, Oxenius, Annette, Regoes, Roland R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416789/
https://www.ncbi.nlm.nih.gov/pubmed/25933039
http://dx.doi.org/10.1371/journal.pcbi.1004178

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