NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cells

Recently approved chemotherapeutic agents to treat colorectal cancer (CRC) have made some impact; however, there is an urgent need for newer targeted agents and strategies to circumvent CRC growth and metastasis. CRC frequently exhibits natural resistance to chemotherapy and those who do respond ini...

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Detalles Bibliográficos
Autores principales: Jaiswal, Aruna S., Panda, Harekrushna, Law, Brian K., Sharma, Jay, Jani, Jitesh, Hromas, Robert, Narayan, Satya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416822/
https://www.ncbi.nlm.nih.gov/pubmed/25933036
http://dx.doi.org/10.1371/journal.pone.0123808

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