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Golgi Anti-apoptotic Proteins Are Highly Conserved Ion Channels That Affect Apoptosis and Cell Migration

Golgi anti-apoptotic proteins (GAAPs) are multitransmembrane proteins that are expressed in the Golgi apparatus and are able to homo-oligomerize. They are highly conserved throughout eukaryotes and are present in some prokaryotes and orthopoxviruses. Within eukaryotes, GAAPs regulate the Ca(2+) cont...

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Detalles Bibliográficos
Autores principales: Carrara, Guia, Saraiva, Nuno, Parsons, Maddy, Byrne, Bernadette, Prole, David L., Taylor, Colin W., Smith, Geoffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416878/
https://www.ncbi.nlm.nih.gov/pubmed/25713081
http://dx.doi.org/10.1074/jbc.M115.637306