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An Epigenome-Wide Association Study of Total Serum Immunoglobulin E Concentration

Immunoglobulin E (IgE) is a central mediator of allergic (atopic) inflammation. Therapies directed against IgE benefit hay fever(1) and allergic asthma(1,2). Genetic association studies have not yet identified novel therapeutic targets or pathways underlying IgE regulation(3-6). We therefore surveye...

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Detalles Bibliográficos
Autores principales:	Liang, Liming, Willis-Owen, Saffron A.G., Laprise, Catherine, Wong, Kenny C.C., Davies, Gwyneth A., Hudson, Thomas J., Binia, Aristea, Hopkin, Julian M., Yang, Ivana V., Grundberg, Elin, Busche, Stephan, Hudson, Marie, Rönnblom, Lars, Pastinen, Tomi M., Schwartz, David A., Lathrop, G. Mark, Moffatt, Miriam F., Cookson, William O.C.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416961/ https://www.ncbi.nlm.nih.gov/pubmed/25707804 http://dx.doi.org/10.1038/nature14125

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