Cargando…
The ITIM-containing receptor LAIR1 is essential for acute myeloid leukemia development
Conventional strategies are not particularly successful in treatment of leukemia, and identification of signaling pathways crucial to the activity of leukemia stem cells will provide targets for the development of new therapies. Here we report that certain receptors containing the immunoreceptor tyr...
Autores principales: | Kang, Xunlei, Lu, Zhigang, Cui, Changhao, Deng, Mi, Fan, Yuqi, Dong, Baijun, Han, Xin, Xie, Fuchun, Tyner, Jeffrey W., Coligan, John E., Collins, Robert H., Xiao, Xiangshu, You, M. James, Zhang, Cheng Cheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417000/ https://www.ncbi.nlm.nih.gov/pubmed/25915125 http://dx.doi.org/10.1038/ncb3158 |
Ejemplares similares
-
LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological Neoplasms
por: Van Laethem, François, et al.
Publicado: (2022) -
The ITIM-Containing Receptor: Leukocyte-Associated Immunoglobulin-Like Receptor-1 (LAIR-1) Modulates Immune Response and Confers Poor Prognosis in Invasive Breast Carcinoma
por: Joseph, Chitra, et al.
Publicado: (2020) -
LAIR-1 agonism as a therapy for acute myeloid leukemia
por: Lovewell, Rustin R., et al.
Publicado: (2023) -
CAMKs support development of acute myeloid leukemia
por: Kang, Xunlei, et al.
Publicado: (2018) -
Gargamelle's new lair
Publicado: (1975)