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Germline and somatic imprinting in the nonhuman primate highlights species differences in oocyte methylation

Genomic imprinting is an epigenetic mechanism resulting in parental allele-specific gene expression. Defects in normal imprinting are found in cancer, assisted reproductive technologies, and several human syndromes. In mouse models, germline-derived DNA methylation is shown to regulate imprinting. T...

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Detalles Bibliográficos
Autores principales: Cheong, Clara Y., Chng, Keefe, Ng, Shilen, Chew, Siew Boom, Chan, Louiza, Ferguson-Smith, Anne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417110/
https://www.ncbi.nlm.nih.gov/pubmed/25862382
http://dx.doi.org/10.1101/gr.183301.114

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