Accurate typing of short tandem repeats from genome-wide sequencing data and its applications

Short tandem repeats (STRs) are implicated in dozens of human genetic diseases and contribute significantly to genome variation and instability. Yet profiling STRs from short-read sequencing data is challenging because of their high sequencing error rates. Here, we developed STR-FM, short tandem rep...

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Detalles Bibliográficos
Autores principales: Fungtammasan, Arkarachai, Ananda, Guruprasad, Hile, Suzanne E., Su, Marcia Shu-Wei, Sun, Chen, Harris, Robert, Medvedev, Paul, Eckert, Kristin, Makova, Kateryna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417121/
https://www.ncbi.nlm.nih.gov/pubmed/25823460
http://dx.doi.org/10.1101/gr.185892.114

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