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Integrating motif, DNA accessibility and gene expression data to build regulatory maps in an organism

Characterization of cell type specific regulatory networks and elements is a major challenge in genomics, and emerging strategies frequently employ high-throughput genome-wide assays of transcription factor (TF) to DNA binding, histone modifications or chromatin state. However, these experiments rem...

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Detalles Bibliográficos
Autores principales: Blatti, Charles, Kazemian, Majid, Wolfe, Scot, Brodsky, Michael, Sinha, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417154/
https://www.ncbi.nlm.nih.gov/pubmed/25791631
http://dx.doi.org/10.1093/nar/gkv195