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Integrating motif, DNA accessibility and gene expression data to build regulatory maps in an organism
Characterization of cell type specific regulatory networks and elements is a major challenge in genomics, and emerging strategies frequently employ high-throughput genome-wide assays of transcription factor (TF) to DNA binding, histone modifications or chromatin state. However, these experiments rem...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417154/ https://www.ncbi.nlm.nih.gov/pubmed/25791631 http://dx.doi.org/10.1093/nar/gkv195 |