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Regulation of yeast DNA polymerase δ-mediated strand displacement synthesis by 5′-flaps

The strand displacement activity of DNA polymerase δ is strongly stimulated by its interaction with proliferating cell nuclear antigen (PCNA). However, inactivation of the 3′–5′ exonuclease activity is sufficient to allow the polymerase to carry out strand displacement even in the absence of PCNA. W...

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Detalles Bibliográficos
Autores principales:	Koc, Katrina N., Stodola, Joseph L., Burgers, Peter M., Galletto, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417170/ https://www.ncbi.nlm.nih.gov/pubmed/25813050 http://dx.doi.org/10.1093/nar/gkv260

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