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A universal strategy for regulating mRNA translation in prokaryotic and eukaryotic cells

We describe a simple strategy to control mRNA translation in both prokaryotic and eukaryotic cells which relies on a unique protein–RNA interaction. Specifically, we used the Pumilio/FBF (PUF) protein to repress translation by binding in between the ribosome binding site (RBS) and the start codon (i...

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Detalles Bibliográficos
Autores principales:	Cao, Jicong, Arha, Manish, Sudrik, Chaitanya, Mukherjee, Abhirup, Wu, Xia, Kane, Ravi S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417184/ https://www.ncbi.nlm.nih.gov/pubmed/25845589 http://dx.doi.org/10.1093/nar/gkv290

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