Irisin: a new molecular marker and target in metabolic disorder

Irisin is a newly discovered exercise-mediated myokine which regulates energy metabolism and has been the subject of much recent research. Irisin plays an important role in metabolic diseases making it a potential new target to combat obesity and its associated disorders, such as T2DM. However, the...

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Detalles Bibliográficos
Autores principales: Chen, Jia-qi, Huang, Yue-ye, Gusdon, Aaron M, Qu, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417264/
https://www.ncbi.nlm.nih.gov/pubmed/25588692
http://dx.doi.org/10.1186/1476-511X-14-2
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author Chen, Jia-qi
Huang, Yue-ye
Gusdon, Aaron M
Qu, Shen
author_facet Chen, Jia-qi
Huang, Yue-ye
Gusdon, Aaron M
Qu, Shen
author_sort Chen, Jia-qi
collection PubMed
description Irisin is a newly discovered exercise-mediated myokine which regulates energy metabolism and has been the subject of much recent research. Irisin plays an important role in metabolic diseases making it a potential new target to combat obesity and its associated disorders, such as T2DM. However, the results of several recent studies investigating the effects of irisin have been controversial. The present review will introduce the discovery of irisin, the role of irisin in metabolic disorders, possible mechanisms, and unanswered questions for future research.
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spelling pubmed-44172642015-05-03 Irisin: a new molecular marker and target in metabolic disorder Chen, Jia-qi Huang, Yue-ye Gusdon, Aaron M Qu, Shen Lipids Health Dis Review Irisin is a newly discovered exercise-mediated myokine which regulates energy metabolism and has been the subject of much recent research. Irisin plays an important role in metabolic diseases making it a potential new target to combat obesity and its associated disorders, such as T2DM. However, the results of several recent studies investigating the effects of irisin have been controversial. The present review will introduce the discovery of irisin, the role of irisin in metabolic disorders, possible mechanisms, and unanswered questions for future research. BioMed Central 2015-01-14 /pmc/articles/PMC4417264/ /pubmed/25588692 http://dx.doi.org/10.1186/1476-511X-14-2 Text en © Chen et al.; licensee BioMed Central. 2015 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Chen, Jia-qi
Huang, Yue-ye
Gusdon, Aaron M
Qu, Shen
Irisin: a new molecular marker and target in metabolic disorder
title Irisin: a new molecular marker and target in metabolic disorder
title_full Irisin: a new molecular marker and target in metabolic disorder
title_fullStr Irisin: a new molecular marker and target in metabolic disorder
title_full_unstemmed Irisin: a new molecular marker and target in metabolic disorder
title_short Irisin: a new molecular marker and target in metabolic disorder
title_sort irisin: a new molecular marker and target in metabolic disorder
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417264/
https://www.ncbi.nlm.nih.gov/pubmed/25588692
http://dx.doi.org/10.1186/1476-511X-14-2
work_keys_str_mv AT chenjiaqi irisinanewmolecularmarkerandtargetinmetabolicdisorder
AT huangyueye irisinanewmolecularmarkerandtargetinmetabolicdisorder
AT gusdonaaronm irisinanewmolecularmarkerandtargetinmetabolicdisorder
AT qushen irisinanewmolecularmarkerandtargetinmetabolicdisorder

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