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Factors to preserve CpG-rich sequences in methylated CpG islands

BACKGROUND: Mammalian CpG islands (CGIs) normally escape DNA methylation in all adult tissues and developmental stages. However, in our previous study we unexpectedly identified many methylated CGIs in human peripheral blood leukocytes. Methylated CpG dinucleotides convert to TpG dinucleotides throu...

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Detalles Bibliográficos
Autores principales:	Miyahara, Hiroki, Hirose, Osamu, Satou, Kenji, Yamada, Yoichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417305/ https://www.ncbi.nlm.nih.gov/pubmed/25879481 http://dx.doi.org/10.1186/s12864-015-1286-x

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