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Structural and functional changes in maternal left ventricle during pregnancy: a three-dimensional speckle-tracking echocardiography study
BACKGROUND: Pregnancy represents a physiological adaptation to the transient load changes of maternal heart. This study aimed to investigate maternal left ventricle (LV) performance during normal pregnancy by three-dimensional speckle-tracking echocardiography (3D STE) parameters considering LV load...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417318/ https://www.ncbi.nlm.nih.gov/pubmed/25626356 http://dx.doi.org/10.1186/1476-7120-13-6 |
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author | Cong, Juan Fan, Tingpan Yang, Xiaoqian Squires, Jared Wynn Cheng, Guomei Zhang, Linlin Zhang, Zhan |
author_facet | Cong, Juan Fan, Tingpan Yang, Xiaoqian Squires, Jared Wynn Cheng, Guomei Zhang, Linlin Zhang, Zhan |
author_sort | Cong, Juan |
collection | PubMed |
description | BACKGROUND: Pregnancy represents a physiological adaptation to the transient load changes of maternal heart. This study aimed to investigate maternal left ventricle (LV) performance during normal pregnancy by three-dimensional speckle-tracking echocardiography (3D STE) parameters considering LV loading and shape. METHODS: Sequential two-dimensional echocardiography (2DE) and 3D STE were performed on 68 women during each pregnancy trimester and 6 to 9 weeks after delivery, while thirty age-matched, healthy, nonpregnant women served as controls. Global longitudinal strain (GLS), global circumferential strain (GCS), global area strain (GAS) and global radial strain (GRS) were measured. RESULTS: Increased cardiac index and progressive eccentric hypertrophy was detected, which subsequently recovered postpartum. In late pregnancy, GLS, GCS, GAS and GRS significantly decreased (P < 0.05) accompanied by a slight reduction of LV ejection fraction (EF) (P < 0.05), and these values returned postpartum to baseline level. All 3D strain indices correlated well with gestation age (P < 0.01), while compared to other components, GAS exhibited the strongest association with 3D EF (r = 0.549) and sphericity index (r = 0.328), and was the only parameter that correlated well with LV mass index (r = 0.22). CONCLUSIONS: This study gives normal ranges of 3D STE indices in pregnancy. 3D STE demonstrated modified myocardial deformation and changes in maternal LV structure and function during the gestation period. |
format | Online Article Text |
id | pubmed-4417318 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-44173182015-05-03 Structural and functional changes in maternal left ventricle during pregnancy: a three-dimensional speckle-tracking echocardiography study Cong, Juan Fan, Tingpan Yang, Xiaoqian Squires, Jared Wynn Cheng, Guomei Zhang, Linlin Zhang, Zhan Cardiovasc Ultrasound Research BACKGROUND: Pregnancy represents a physiological adaptation to the transient load changes of maternal heart. This study aimed to investigate maternal left ventricle (LV) performance during normal pregnancy by three-dimensional speckle-tracking echocardiography (3D STE) parameters considering LV loading and shape. METHODS: Sequential two-dimensional echocardiography (2DE) and 3D STE were performed on 68 women during each pregnancy trimester and 6 to 9 weeks after delivery, while thirty age-matched, healthy, nonpregnant women served as controls. Global longitudinal strain (GLS), global circumferential strain (GCS), global area strain (GAS) and global radial strain (GRS) were measured. RESULTS: Increased cardiac index and progressive eccentric hypertrophy was detected, which subsequently recovered postpartum. In late pregnancy, GLS, GCS, GAS and GRS significantly decreased (P < 0.05) accompanied by a slight reduction of LV ejection fraction (EF) (P < 0.05), and these values returned postpartum to baseline level. All 3D strain indices correlated well with gestation age (P < 0.01), while compared to other components, GAS exhibited the strongest association with 3D EF (r = 0.549) and sphericity index (r = 0.328), and was the only parameter that correlated well with LV mass index (r = 0.22). CONCLUSIONS: This study gives normal ranges of 3D STE indices in pregnancy. 3D STE demonstrated modified myocardial deformation and changes in maternal LV structure and function during the gestation period. BioMed Central 2015-01-27 /pmc/articles/PMC4417318/ /pubmed/25626356 http://dx.doi.org/10.1186/1476-7120-13-6 Text en © Cong et al.; licensee BioMed Central. 2015 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Cong, Juan Fan, Tingpan Yang, Xiaoqian Squires, Jared Wynn Cheng, Guomei Zhang, Linlin Zhang, Zhan Structural and functional changes in maternal left ventricle during pregnancy: a three-dimensional speckle-tracking echocardiography study |
title | Structural and functional changes in maternal left ventricle during pregnancy: a three-dimensional speckle-tracking echocardiography study |
title_full | Structural and functional changes in maternal left ventricle during pregnancy: a three-dimensional speckle-tracking echocardiography study |
title_fullStr | Structural and functional changes in maternal left ventricle during pregnancy: a three-dimensional speckle-tracking echocardiography study |
title_full_unstemmed | Structural and functional changes in maternal left ventricle during pregnancy: a three-dimensional speckle-tracking echocardiography study |
title_short | Structural and functional changes in maternal left ventricle during pregnancy: a three-dimensional speckle-tracking echocardiography study |
title_sort | structural and functional changes in maternal left ventricle during pregnancy: a three-dimensional speckle-tracking echocardiography study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417318/ https://www.ncbi.nlm.nih.gov/pubmed/25626356 http://dx.doi.org/10.1186/1476-7120-13-6 |
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