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Induction of the intrinsic apoptotic pathway via a new antimitotic agent in an esophageal carcinoma cell line
BACKGROUND: 2-Ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16) is a unique, in silico-designed compound with possible anticancer properties, which were identified in our laboratory. This compound is capable of interfering with microtubule dynamics and is believed to have potential carbonic a...
Autores principales: | Wolmarans, Elize, Sippel, Katherine, McKenna, Robert, Joubert, Annie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417530/ https://www.ncbi.nlm.nih.gov/pubmed/25937890 http://dx.doi.org/10.1186/2045-3701-4-68 |
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