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Evaluation of Electron Contamination in Cancer Treatment with Megavoltage Photon Beams: Monte Carlo Study

BACKGROUND: Megavoltage beams used in radiotherapy are contaminated with secondary electrons. Different parts of linac head and air above patient act as a source of this contamination. This contamination can increase damage to skin and subcutaneous tissue during radiotherapy. Monte Carlo simulation...

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Autores principales: Seif, F., Bayatiani, M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417618/
https://www.ncbi.nlm.nih.gov/pubmed/25973409
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author Seif, F.
Bayatiani, M. R.
author_facet Seif, F.
Bayatiani, M. R.
author_sort Seif, F.
collection PubMed
description BACKGROUND: Megavoltage beams used in radiotherapy are contaminated with secondary electrons. Different parts of linac head and air above patient act as a source of this contamination. This contamination can increase damage to skin and subcutaneous tissue during radiotherapy. Monte Carlo simulation is an accurate method for dose calculation in medical dosimetry and has an important role in optimization of linac head materials. The aim of this study was to calculate electron contamination of Varian linac. MATERIALS AND METHOD: The 6MV photon beam of Varian (2100 C/D) linac was simulated by Monte Carlo code, MCNPX, based on its company’s instructions. The validation was done by comparing the calculated depth dose and profiles of simulation with dosimetry measurements in a water phantom (error less than 2%). The Percentage Depth Dose (PDDs), profiles and contamination electron energy spectrum were calculated for different therapeutic field sizes (5×5 to 40×40 cm(2)) for both linacs. RESULTS: The dose of electron contamination was observed to rise with increase in field size. The contribution of the secondary contamination electrons on the surface dose was 6% for 5×5 cm(2) to 27% for 40×40 cm(2), respectively. CONCLUSION: Based on the results, the effect of electron contamination on patient surface dose cannot be ignored, so the knowledge of the electron contamination is important in clinical dosimetry. It must be calculated for each machine and considered in Treatment Planning Systems.
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spelling pubmed-44176182015-05-13 Evaluation of Electron Contamination in Cancer Treatment with Megavoltage Photon Beams: Monte Carlo Study Seif, F. Bayatiani, M. R. J Biomed Phys Eng Original Article BACKGROUND: Megavoltage beams used in radiotherapy are contaminated with secondary electrons. Different parts of linac head and air above patient act as a source of this contamination. This contamination can increase damage to skin and subcutaneous tissue during radiotherapy. Monte Carlo simulation is an accurate method for dose calculation in medical dosimetry and has an important role in optimization of linac head materials. The aim of this study was to calculate electron contamination of Varian linac. MATERIALS AND METHOD: The 6MV photon beam of Varian (2100 C/D) linac was simulated by Monte Carlo code, MCNPX, based on its company’s instructions. The validation was done by comparing the calculated depth dose and profiles of simulation with dosimetry measurements in a water phantom (error less than 2%). The Percentage Depth Dose (PDDs), profiles and contamination electron energy spectrum were calculated for different therapeutic field sizes (5×5 to 40×40 cm(2)) for both linacs. RESULTS: The dose of electron contamination was observed to rise with increase in field size. The contribution of the secondary contamination electrons on the surface dose was 6% for 5×5 cm(2) to 27% for 40×40 cm(2), respectively. CONCLUSION: Based on the results, the effect of electron contamination on patient surface dose cannot be ignored, so the knowledge of the electron contamination is important in clinical dosimetry. It must be calculated for each machine and considered in Treatment Planning Systems. Shiraz University of Medical Sciences 2015-03-04 /pmc/articles/PMC4417618/ /pubmed/25973409 Text en © 2015: Journal of Biomedical Physics and Engineering This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported License (http://creativecommons.org/licenses/by-nc/3.0/deed.en_US), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Seif, F.
Bayatiani, M. R.
Evaluation of Electron Contamination in Cancer Treatment with Megavoltage Photon Beams: Monte Carlo Study
title Evaluation of Electron Contamination in Cancer Treatment with Megavoltage Photon Beams: Monte Carlo Study
title_full Evaluation of Electron Contamination in Cancer Treatment with Megavoltage Photon Beams: Monte Carlo Study
title_fullStr Evaluation of Electron Contamination in Cancer Treatment with Megavoltage Photon Beams: Monte Carlo Study
title_full_unstemmed Evaluation of Electron Contamination in Cancer Treatment with Megavoltage Photon Beams: Monte Carlo Study
title_short Evaluation of Electron Contamination in Cancer Treatment with Megavoltage Photon Beams: Monte Carlo Study
title_sort evaluation of electron contamination in cancer treatment with megavoltage photon beams: monte carlo study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417618/
https://www.ncbi.nlm.nih.gov/pubmed/25973409
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