CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes

Genome editing tools such as the clustered regularly interspaced short palindromic repeat (CRISPR)-associated system (Cas) have been widely used to modify genes in model systems including animal zygotes and human cells, and hold tremendous promise for both basic research and clinical applications. T...

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Detalles Bibliográficos
Autores principales: Liang, Puping, Xu, Yanwen, Zhang, Xiya, Ding, Chenhui, Huang, Rui, Zhang, Zhen, Lv, Jie, Xie, Xiaowei, Chen, Yuxi, Li, Yujing, Sun, Ying, Bai, Yaofu, Songyang, Zhou, Ma, Wenbin, Zhou, Canquan, Huang, Junjiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417674/
https://www.ncbi.nlm.nih.gov/pubmed/25894090
http://dx.doi.org/10.1007/s13238-015-0153-5

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