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SIRTain regulators of premature senescence and accelerated aging

The sirtuin proteins constitute class III histone deacetylases (HDACs). These evolutionarily conserved NAD(+)-dependent enzymes form an important component in a variety of cellular and biological processes with highly divergent as well as convergent roles in maintaining metabolic homeostasis, safegu...

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Detalles Bibliográficos
Autores principales: Ghosh, Shrestha, Zhou, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417679/
https://www.ncbi.nlm.nih.gov/pubmed/25907989
http://dx.doi.org/10.1007/s13238-015-0149-1