Genome Sequence of Classical Swine Fever Virus Genotype 1.1 with a Genetic Marker of Attenuation Detected in a Continuous Porcine Cell Line

The complete genome sequencing and analysis of a classical swine fever virus (CSFV) detected in a porcine kidney cell line revealed a close relationship with genotype 1.1 viruses circulating in India and China. The presence of consecutive T insertions in the 3′ untranslated region (UTR), as seen in...

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Autores principales: Tomar, N., Gupta, A., Arya, R. S., Somvanshi, R., Sharma, V., Saikumar, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Viruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417697/
https://www.ncbi.nlm.nih.gov/pubmed/25931601
http://dx.doi.org/10.1128/genomeA.00375-15
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author Tomar, N.
Gupta, A.
Arya, R. S.
Somvanshi, R.
Sharma, V.
Saikumar, G.
author_facet Tomar, N.
Gupta, A.
Arya, R. S.
Somvanshi, R.
Sharma, V.
Saikumar, G.
author_sort Tomar, N.
collection PubMed
description The complete genome sequencing and analysis of a classical swine fever virus (CSFV) detected in a porcine kidney cell line revealed a close relationship with genotype 1.1 viruses circulating in India and China. The presence of consecutive T insertions in the 3′ untranslated region (UTR), as seen in vaccine strains of CSFV, suggested some degree of attenuation.
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spelling pubmed-44176972015-05-06 Genome Sequence of Classical Swine Fever Virus Genotype 1.1 with a Genetic Marker of Attenuation Detected in a Continuous Porcine Cell Line Tomar, N. Gupta, A. Arya, R. S. Somvanshi, R. Sharma, V. Saikumar, G. Genome Announc Viruses The complete genome sequencing and analysis of a classical swine fever virus (CSFV) detected in a porcine kidney cell line revealed a close relationship with genotype 1.1 viruses circulating in India and China. The presence of consecutive T insertions in the 3′ untranslated region (UTR), as seen in vaccine strains of CSFV, suggested some degree of attenuation. American Society for Microbiology 2015-04-30 /pmc/articles/PMC4417697/ /pubmed/25931601 http://dx.doi.org/10.1128/genomeA.00375-15 Text en Copyright © 2015 Tomar et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Viruses
Tomar, N.
Gupta, A.
Arya, R. S.
Somvanshi, R.
Sharma, V.
Saikumar, G.
Genome Sequence of Classical Swine Fever Virus Genotype 1.1 with a Genetic Marker of Attenuation Detected in a Continuous Porcine Cell Line
title Genome Sequence of Classical Swine Fever Virus Genotype 1.1 with a Genetic Marker of Attenuation Detected in a Continuous Porcine Cell Line
title_full Genome Sequence of Classical Swine Fever Virus Genotype 1.1 with a Genetic Marker of Attenuation Detected in a Continuous Porcine Cell Line
title_fullStr Genome Sequence of Classical Swine Fever Virus Genotype 1.1 with a Genetic Marker of Attenuation Detected in a Continuous Porcine Cell Line
title_full_unstemmed Genome Sequence of Classical Swine Fever Virus Genotype 1.1 with a Genetic Marker of Attenuation Detected in a Continuous Porcine Cell Line
title_short Genome Sequence of Classical Swine Fever Virus Genotype 1.1 with a Genetic Marker of Attenuation Detected in a Continuous Porcine Cell Line
title_sort genome sequence of classical swine fever virus genotype 1.1 with a genetic marker of attenuation detected in a continuous porcine cell line
topic Viruses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417697/
https://www.ncbi.nlm.nih.gov/pubmed/25931601
http://dx.doi.org/10.1128/genomeA.00375-15
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