Cargando…

An H5N1-based matrix protein 2 ectodomain tetrameric peptide vaccine provides cross-protection against lethal infection with H7N9 influenza virus

In March 2013, a patient infected with a novel avian influenza A H7N9 virus was reported in China. Since then, there have been 458 confirmed infection cases and 177 deaths. The virus contains several human-adapted markers, indicating that H7N9 has pandemic potential. The outbreak of this new influen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leung, Ho-Chuen, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Zhao, Han-Jun, Cheung, Chung-Yan, Ng, Fai, Huang, Jian-Dong, Zheng, Bo-Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417706/ https://www.ncbi.nlm.nih.gov/pubmed/26038770 http://dx.doi.org/10.1038/emi.2015.22

Ejemplares similares

Virus-Like Particles Containing the Tetrameric Ectodomain of Influenza Matrix Protein 2 and Flagellin Induce Heterosubtypic Protection in Mice
por: Wang, Li, et al.
Publicado: (2013)

A Recombinant Vaccine of H5N1 HA1 Fused with Foldon and Human IgG Fc Induced Complete Cross-Clade Protection against Divergent H5N1 Viruses
por: Du, Lanying, et al.
Publicado: (2011)

A single dose of DNA vaccine based on conserved H5N1 subtype proteins provides protection against lethal H5N1 challenge in mice pre-exposed to H1N1 influenza virus
por: Chang, Haiyan, et al.
Publicado: (2010)

Loop-Mediated Isothermal Amplification for Influenza A (H5N1) Virus
por: Jayawardena, Shanthi, et al.
Publicado: (2007)

Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation
por: Conant, Katherine, et al.
Publicado: (2017)

The Therapeutic Effect of Pamidronate on Lethal Avian Influenza A H7N9 Virus Infected Humanized Mice
por: Zheng, Jian, et al.
Publicado: (2015)

Properly Folded Bacterially Expressed H1N1 Hemagglutinin Globular Head and Ectodomain Vaccines Protect Ferrets against H1N1 Pandemic Influenza Virus
por: Khurana, Surender, et al.
Publicado: (2010)

Rapid Detection of Reassortment of Pandemic H1N1/2009 Influenza Virus
por: Poon, Leo L M, et al.
Publicado: (2010)

Antibody-Dependent Cell-Mediated Cytotoxicity Epitopes on the Hemagglutinin Head Region of Pandemic H1N1 Influenza Virus Play Detrimental Roles in H1N1-Infected Mice
por: Ye, Zi-Wei, et al.
Publicado: (2017)

Human H7N9 avian influenza virus infection: a review and pandemic risk assessment
por: Yiu Lai, Kang, et al.
Publicado: (2013)

Human H7N9 avian influenza virus infection: a review and pandemic risk assessment
por: Yiu Lai, Kang, et al.
Publicado: (2013)

Production of H5N1 Influenza Virus Matrix Protein 2 Ectodomain Protein Bodies in Tobacco Plants and in Insect Cells as a Candidate Universal Influenza Vaccine
por: Mbewana, Sandiswa, et al.
Publicado: (2015)

Inactivated H5 Antigens of H5N8 Protect Chickens from Lethal Infections by the Highly Pathogenic H5N8 and H5N6 Avian Influenza Viruses
por: Jin, Myongha, et al.
Publicado: (2018)

MVA Vectors Expressing Conserved Influenza Proteins Protect Mice against Lethal Challenge with H5N1, H9N2 and H7N1 Viruses
por: Hessel, Annett, et al.
Publicado: (2014)

Effect of avian influenza A H5N1 infection on the expression of microRNA-141 in human respiratory epithelial cells
por: Lam, Wai-Yip, et al.
Publicado: (2013)

TdfH selectively binds metal-loaded tetrameric calprotectin for zinc import
por: Bera, Aloke K., et al.
Publicado: (2022)

Wild Type and Mutant 2009 Pandemic Influenza A (H1N1) Viruses Cause More Severe Disease and Higher Mortality in Pregnant BALB/c Mice
por: Chan, Kwok-Hung, et al.
Publicado: (2010)

Mass spectrometry data confirming tetrameric α-synuclein N-terminal acetylation
por: Fernández, Ricardo D., et al.
Publicado: (2018)

Influenza H7N9 Virus Hemagglutinin with T169A Mutation Possesses Enhanced Thermostability and Provides Effective Immune Protection against Lethal H7N9 Virus Challenge in Chickens
por: Chen, Taoran, et al.
Publicado: (2023)

Complete Genome Sequence of an H9N2 Influenza Virus Lethal to Chickens
por: Zhang, Yi, et al.
Publicado: (2014)

A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses
por: Zhao, Hanjun, et al.
Publicado: (2016)

Oligomerization of the SARS-CoV S glycoprotein: dimerization of the N-terminus and trimerization of the ectodomain
por: Xiao, Xiaodong, et al.
Publicado: (2004)

Human Avian Influenza A H5N1, H7N9, H10N8 and H5N6 Virus Infection
por: Lu, Pu-Xuan, et al.
Publicado: (2015)

An H5N1 M2e-based multiple antigenic peptide vaccine confers heterosubtypic protection from lethal infection with pandemic 2009 H1N1 virus
por: Zhao, Guangyu, et al.
Publicado: (2010)

Matrix‐M adjuvanted virosomal H5N1 vaccine confers protection against lethal viral challenge in a murine model
por: Pedersen, Gabriel, et al.
Publicado: (2011)

The Histone Chaperones Nap1 and Vps75 Bind Histones H3 and H4 in a Tetrameric Conformation
por: Bowman, Andrew, et al.
Publicado: (2011)

Oseltamivir-Resistant Influenza A Pandemic (H1N1) 2009 Virus, Hong Kong, China
por: Chen, Honglin, et al.
Publicado: (2009)

N-Linked glycosylation of the membrane protein ectodomain regulates infectious bronchitis virus-induced ER stress response, apoptosis and pathogenesis
por: Liang, Jia Qi, et al.
Publicado: (2019)

Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters
por: Zhang, Anna Jinxia, et al.
Publicado: (2020)

Increased Inflammatory Signaling and Lethality of Influenza H1N1 by Nuclear Thioredoxin-1
por: Go, Young-Mi, et al.
Publicado: (2011)

Amino Acid Substitutions Improve the Immunogenicity of H7N7HA Protein and Protect Mice against Lethal H7N7 Viral Challenge
por: kumar, Subaschandrabose Rajesh, et al.
Publicado: (2015)

Age- Matched Comparison of Children Hospitalized for 2009 Pandemic H1N1 Influenza with Those Hospitalized for Seasonal H1N1 and H3N2
por: Chiu, Susan S., et al.
Publicado: (2011)

The Role of Matrix Protein 2 Ectodomain in the Development of Universal Influenza Vaccines
por: Saelens, Xavier
Publicado: (2019)

Suppressive effect of syndecan ectodomains and N-desulfated heparins on osteoclastogenesis via direct binding to macrophage-colony stimulating factor
por: Kim, Jin-Man, et al.
Publicado: (2018)

Re-emergence of fatal human influenza A subtype H5N1 disease
por: Peiris, JSM, et al.
Publicado: (2004)

Influenza Antigens NP and M2 Confer Cross Protection to BALB/c Mice against Lethal Challenge with H1N1, Pandemic H1N1 or H5N1 Influenza A Viruses
por: Mytle, Nutan, et al.
Publicado: (2021)

Inhibition of the inflammatory cytokine tumor necrosis factor-alpha with etanercept provides protection against lethal H1N1 influenza infection in mice
por: Shi, Xunlong, et al.
Publicado: (2013)

T cell mediated immunity against influenza H5N1 nucleoprotein, matrix and hemagglutinin derived epitopes in H5N1 survivors and non-H5N1 subjects
por: Noisumdaeng, Pirom, et al.
Publicado: (2021)

The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones
por: Liu, Wallace H, et al.
Publicado: (2016)

Live attenuated H5N1 vaccine with H9N2 internal genes protects chickens from infections by both Highly Pathogenic H5N1 and H9N2 Influenza Viruses
por: Nang, Nguyen Tai, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_s2ntoll4n489p55j9l8ij5ojma