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Polyphenols isolated from Broussonetia kazinoki prevent cytokine-induced β-cell damage and the development of type 1 diabetes
The axis of nuclear factor κB (NF-κB)-inducible NO synthase (iNOS)-nitric oxide plays a key role in cytokine- and streptozotocin-mediated pancreatic β-cell damage. In this study, we investigated the effects of kazinol C and isokazinol D isolated from Broussonetia kazinoki on the β-cell viability and...
Autores principales: | Bae, Ui-Jin, Jang, Hyun-Young, Lim, Jung Min, Hua, Li, Ryu, Jae-Ha, Park, Byung-Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418042/ https://www.ncbi.nlm.nih.gov/pubmed/25907110 http://dx.doi.org/10.1038/emm.2015.16 |
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