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Issues Related to Obtaining Intelligence Quotient-Matched Controls in Autism Research

BACKGROUND: Intelligence Quotient (IQ) is considered to be an index of global cognitive functioning and has traditionally been used as a fulcral measure in case-control studies in neuro-developmental disorders such as autism. AIM: The aim is to highlight the issues of “matching for IQ” with controls...

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Detalles Bibliográficos
Autores principales: Rao, Vanitha S., Raman, Vijaya, Mysore, Ashok V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418245/
https://www.ncbi.nlm.nih.gov/pubmed/25969598
http://dx.doi.org/10.4103/0253-7176.155612
Descripción
Sumario:BACKGROUND: Intelligence Quotient (IQ) is considered to be an index of global cognitive functioning and has traditionally been used as a fulcral measure in case-control studies in neuro-developmental disorders such as autism. AIM: The aim is to highlight the issues of “matching for IQ” with controls in autism research. MATERIALS AND METHODS: Percentile scores on the Coloured Progressive Matrices of 20 children with autism in the age range of 5 to 12 years have been graphically compared with 21 age matched typically developing children. RESULTS AND CONCLUSIONS: The percentile scores of the so-called high functioning children with autism from special schools were well below that of typically developing children. There are many challenges when using IQ in case-control studies of autism. Alternative approaches need to be considered.