Coagulation factor XII protease domain crystal structure

BACKGROUND: Coagulation factor XII is a serine protease that is important for kinin generation and blood coagulation, cleaving the substrates plasma kallikrein and FXI. OBJECTIVE: To investigate FXII zymogen activation and substrate recognition by determining the crystal structure of the FXII protea...

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Detalles Bibliográficos
Autores principales: Pathak, M, Wilmann, P, Awford, J, Li, C, Hamad, BK, Fischer, PM, Dreveny, I, Dekker, LV, Emsley, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Coagulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418343/
https://www.ncbi.nlm.nih.gov/pubmed/25604127
http://dx.doi.org/10.1111/jth.12849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418343/
https://www.ncbi.nlm.nih.gov/pubmed/25604127
http://dx.doi.org/10.1111/jth.12849

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