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Coagulation factor XII protease domain crystal structure

BACKGROUND: Coagulation factor XII is a serine protease that is important for kinin generation and blood coagulation, cleaving the substrates plasma kallikrein and FXI. OBJECTIVE: To investigate FXII zymogen activation and substrate recognition by determining the crystal structure of the FXII protea...

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Detalles Bibliográficos
Autores principales:	Pathak, M, Wilmann, P, Awford, J, Li, C, Hamad, BK, Fischer, PM, Dreveny, I, Dekker, LV, Emsley, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2015
Materias:	Coagulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418343/ https://www.ncbi.nlm.nih.gov/pubmed/25604127 http://dx.doi.org/10.1111/jth.12849

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