Pharmacokinetics of the Dual Melatonin Receptor Agonist Tasimelteon in Subjects With Hepatic or Renal Impairment

Tasimelteon is a circadian regulator that resets the master clock in the suprachiasmatic nuclei of the hypothalamus by binding to both melatonin MT(1) and MT(2) receptors making it a dual melatonin receptor agonist. Tasimelteon has been approved by the United States Food and Drug Administration for...

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Detalles Bibliográficos
Autores principales: Torres, Rosarelis, Kramer, William G, Baroldi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Special Populations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418347/
https://www.ncbi.nlm.nih.gov/pubmed/25450415
http://dx.doi.org/10.1002/jcph.440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418347/
https://www.ncbi.nlm.nih.gov/pubmed/25450415
http://dx.doi.org/10.1002/jcph.440

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