Two new amides from a halotolerant fungus, Myrothecium sp. GS-17

Two new amides, named N-acetyl-2,4,10,17-tetrahydroxyheptadecylamine (1) and N-acetyl-3,5,11,18-tetrahydroxyoctadecyl-2-amine (2), were isolated from a halotolerant fungus, Myrothecium sp. GS-17. Their structures were identified on the basis of spectroscopic characteristics. The cancer cell cytotoxi...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Tao, Zhang, Songya, Zhu, Jing, Pan, Huaqi, Bai, Jiao, Li, Zhanlin, Guan, Liping, Liu, Guyue, Yuan, Chunmao, Wu, Xin, Hua, Huiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418385/
https://www.ncbi.nlm.nih.gov/pubmed/25269461
http://dx.doi.org/10.1038/ja.2014.136
Descripción
Sumario:Two new amides, named N-acetyl-2,4,10,17-tetrahydroxyheptadecylamine (1) and N-acetyl-3,5,11,18-tetrahydroxyoctadecyl-2-amine (2), were isolated from a halotolerant fungus, Myrothecium sp. GS-17. Their structures were identified on the basis of spectroscopic characteristics. The cancer cell cytotoxicities of two compounds were evaluated, and compound 2 exhibited weak cytotoxicity in HL-60 cell line.

Ejemplares similares