Two new amides from a halotolerant fungus, Myrothecium sp. GS-17

Two new amides, named N-acetyl-2,4,10,17-tetrahydroxyheptadecylamine (1) and N-acetyl-3,5,11,18-tetrahydroxyoctadecyl-2-amine (2), were isolated from a halotolerant fungus, Myrothecium sp. GS-17. Their structures were identified on the basis of spectroscopic characteristics. The cancer cell cytotoxi...

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Autores principales: Liu, Tao, Zhang, Songya, Zhu, Jing, Pan, Huaqi, Bai, Jiao, Li, Zhanlin, Guan, Liping, Liu, Guyue, Yuan, Chunmao, Wu, Xin, Hua, Huiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418385/
https://www.ncbi.nlm.nih.gov/pubmed/25269461
http://dx.doi.org/10.1038/ja.2014.136
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author Liu, Tao
Zhang, Songya
Zhu, Jing
Pan, Huaqi
Bai, Jiao
Li, Zhanlin
Guan, Liping
Liu, Guyue
Yuan, Chunmao
Wu, Xin
Hua, Huiming
author_facet Liu, Tao
Zhang, Songya
Zhu, Jing
Pan, Huaqi
Bai, Jiao
Li, Zhanlin
Guan, Liping
Liu, Guyue
Yuan, Chunmao
Wu, Xin
Hua, Huiming
author_sort Liu, Tao
collection PubMed
description Two new amides, named N-acetyl-2,4,10,17-tetrahydroxyheptadecylamine (1) and N-acetyl-3,5,11,18-tetrahydroxyoctadecyl-2-amine (2), were isolated from a halotolerant fungus, Myrothecium sp. GS-17. Their structures were identified on the basis of spectroscopic characteristics. The cancer cell cytotoxicities of two compounds were evaluated, and compound 2 exhibited weak cytotoxicity in HL-60 cell line.
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spelling pubmed-44183852015-05-12 Two new amides from a halotolerant fungus, Myrothecium sp. GS-17 Liu, Tao Zhang, Songya Zhu, Jing Pan, Huaqi Bai, Jiao Li, Zhanlin Guan, Liping Liu, Guyue Yuan, Chunmao Wu, Xin Hua, Huiming J Antibiot (Tokyo) Original Article Two new amides, named N-acetyl-2,4,10,17-tetrahydroxyheptadecylamine (1) and N-acetyl-3,5,11,18-tetrahydroxyoctadecyl-2-amine (2), were isolated from a halotolerant fungus, Myrothecium sp. GS-17. Their structures were identified on the basis of spectroscopic characteristics. The cancer cell cytotoxicities of two compounds were evaluated, and compound 2 exhibited weak cytotoxicity in HL-60 cell line. Nature Publishing Group 2015-04 2014-10-01 /pmc/articles/PMC4418385/ /pubmed/25269461 http://dx.doi.org/10.1038/ja.2014.136 Text en Copyright © 2015 Japan Antibiotics Research Association http://creativecommons.org/licenses/by-nc-sa/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
spellingShingle Original Article
Liu, Tao
Zhang, Songya
Zhu, Jing
Pan, Huaqi
Bai, Jiao
Li, Zhanlin
Guan, Liping
Liu, Guyue
Yuan, Chunmao
Wu, Xin
Hua, Huiming
Two new amides from a halotolerant fungus, Myrothecium sp. GS-17
title Two new amides from a halotolerant fungus, Myrothecium sp. GS-17
title_full Two new amides from a halotolerant fungus, Myrothecium sp. GS-17
title_fullStr Two new amides from a halotolerant fungus, Myrothecium sp. GS-17
title_full_unstemmed Two new amides from a halotolerant fungus, Myrothecium sp. GS-17
title_short Two new amides from a halotolerant fungus, Myrothecium sp. GS-17
title_sort two new amides from a halotolerant fungus, myrothecium sp. gs-17
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418385/
https://www.ncbi.nlm.nih.gov/pubmed/25269461
http://dx.doi.org/10.1038/ja.2014.136
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