Fibroblast-Derived Exosomes Contribute to Chemoresistance through Priming Cancer Stem Cells in Colorectal Cancer

Chemotherapy resistance observed in patients with colorectal cancer (CRC) may be related to the presence of cancer stem cells (CSCs), but the underlying mechanism(s) remain unclear. Carcinoma-associated fibroblasts (CAFs) are intimately involved in tumor recurrence, and targeting them increases chem...

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Detalles Bibliográficos
Autores principales: Hu, Yibing, Yan, Chang, Mu, Lei, Huang, Kaiyu, Li, Xiaolan, Tao, Deding, Wu, Yaqun, Qin, Jichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418721/
https://www.ncbi.nlm.nih.gov/pubmed/25938772
http://dx.doi.org/10.1371/journal.pone.0125625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418721/
https://www.ncbi.nlm.nih.gov/pubmed/25938772
http://dx.doi.org/10.1371/journal.pone.0125625

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