Effects of the Selective Stretch-Activated Channel Blocker GsMtx4 on Stretch-Induced Changes in Refractoriness in Isolated Rat Hearts and on Ventricular Premature Beats and Arrhythmias after Coronary Occlusion in Swine

Mechanical factors may contribute to ischemic ventricular arrhythmias. GsMtx4 peptide, a selective stretch-activated channel blocker, inhibits stretch-induced atrial arrhythmias. We aimed to assess whether GsMtx4 protects against ventricular ectopy and arrhythmias following coronary occlusion in swi...

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Detalles Bibliográficos
Autores principales: Barrabés, José A., Inserte, Javier, Agulló, Luis, Rodríguez-Sinovas, Antonio, Alburquerque-Béjar, Juan J., Garcia-Dorado, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418727/
https://www.ncbi.nlm.nih.gov/pubmed/25938516
http://dx.doi.org/10.1371/journal.pone.0125753

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