Cargando…
Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria
Mycobacteria possess different type VII secretion (T7S) systems to secrete proteins across their unusual cell envelope. One of these systems, ESX-5, is only present in slow-growing mycobacteria and responsible for the secretion of multiple substrates. However, the role of ESX-5 substrates in growth...
Autores principales: | Ates, Louis S., Ummels, Roy, Commandeur, Susanna, van der Weerd, Robert, Sparrius, Marion, Weerdenburg, Eveline, Alber, Marina, Kalscheuer, Rainer, Piersma, Sander R., Abdallah, Abdallah M., Abd El Ghany, Moataz, Abdel-Haleem, Alyaa M., Pain, Arnab, Jiménez, Connie R., Bitter, Wilbert, Houben, Edith N.G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418733/ https://www.ncbi.nlm.nih.gov/pubmed/25938982 http://dx.doi.org/10.1371/journal.pgen.1005190 |
Ejemplares similares
-
Integrated transcriptomic and proteomic analysis of pathogenic mycobacteria and their esx-1 mutants reveal secretion-dependent regulation of ESX-1 substrates and WhiB6 as a transcriptional regulator
por: Abdallah, Abdallah M., et al.
Publicado: (2019) -
Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes
por: van Winden, Vincent J. C., et al.
Publicado: (2016) -
Identification of a Novel Conjugative Plasmid in Mycobacteria That Requires Both Type IV and Type VII Secretion
por: Ummels, Roy, et al.
Publicado: (2014) -
Species‐specific secretion of ESX‐5 type VII substrates is determined by the linker 2 of EccC(5)
por: Bunduc, Catalin M., et al.
Publicado: (2020) -
The ESX-1 Substrate PPE68 Has a Key Function in ESX-1-Mediated Secretion in Mycobacterium marinum
por: Damen, Merel P. M., et al.
Publicado: (2022)