Cardiovascular Safety Profile and Clinical Experience With High-Dose Domperidone Therapy for Nausea and Vomiting

INTRODUCTION: Domperidone is a dopamine receptor antagonist with peripheral prokinetic and central antiemetic properties. Prolongation of the QTc interval with chronic use of oral domperidone in standard doses has been reported in the literature. Our goal was to investigate cardiac toxicity in patie...

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Detalles Bibliográficos
Autores principales: Ortiz, Arleen, Cooper, Chad J., Alvarez, Alicia, Gomez, Yvette, Sarosiek, Irene, McCallum, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Journal of the Medical Sciences 2015
Materias:
Clinical Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418779/
https://www.ncbi.nlm.nih.gov/pubmed/25828198
http://dx.doi.org/10.1097/MAJ.0000000000000439

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