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Quantitative Analysis of the Enhanced Permeation and Retention (EPR) Effect

Tumor vasculature is characterized by a variety of abnormalities including irregular architecture, poor lymphatic drainage, and the upregulation of factors that increase the paracellular permeability. The increased permeability is important in mediating the uptake of an intravenously administered dr...

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Detalles Bibliográficos
Autores principales: Wong, Andrew D., Ye, Mao, Ulmschneider, Martin B., Searson, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418820/
https://www.ncbi.nlm.nih.gov/pubmed/25938565
http://dx.doi.org/10.1371/journal.pone.0123461

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