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Quantitative Analysis of the Enhanced Permeation and Retention (EPR) Effect
Tumor vasculature is characterized by a variety of abnormalities including irregular architecture, poor lymphatic drainage, and the upregulation of factors that increase the paracellular permeability. The increased permeability is important in mediating the uptake of an intravenously administered dr...
Autores principales: | Wong, Andrew D., Ye, Mao, Ulmschneider, Martin B., Searson, Peter C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418820/ https://www.ncbi.nlm.nih.gov/pubmed/25938565 http://dx.doi.org/10.1371/journal.pone.0123461 |
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