ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis

Immune control of persistent infection with Mycobacterium tuberculosis (Mtb) requires a sustained pathogen-specific CD4 T cell response; however, the molecular pathways governing the generation and maintenance of Mtb protective CD4 T cells are poorly understood. Using MHCII tetramers, we show that M...

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Detalles Bibliográficos
Autores principales: Moguche, Albanus O., Shafiani, Shahin, Clemons, Corey, Larson, Ryan P., Dinh, Crystal, Higdon, Lauren E., Cambier, C.J., Sissons, James R., Gallegos, Alena M., Fink, Pamela J., Urdahl, Kevin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419347/
https://www.ncbi.nlm.nih.gov/pubmed/25918344
http://dx.doi.org/10.1084/jem.20141518

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