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DUSP4 deficiency caused by promoter hypermethylation drives JNK signaling and tumor cell survival in diffuse large B cell lymphoma

The epigenetic dysregulation of tumor suppressor genes is an important driver of human carcinogenesis. We have combined genome-wide DNA methylation analyses and gene expression profiling after pharmacological DNA demethylation with functional screening to identify novel tumor suppressors in diffuse...

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Detalles Bibliográficos
Autores principales:	Schmid, Corina A., Robinson, Mark D., Scheifinger, Nicole A., Müller, Sebastian, Cogliatti, Sergio, Tzankov, Alexandar, Müller, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419353/ https://www.ncbi.nlm.nih.gov/pubmed/25847947 http://dx.doi.org/10.1084/jem.20141957

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