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Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes

BACKGROUND: Oxygen and glucose metabolism play pivotal roles in many (patho)physiological conditions. In particular, oxygen and glucose deprivation (OGD) during ischemia and stroke results in extensive tissue injury and cell death. RESULTS: Using time-resolved ribosome profiling, we assess gene expr...

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Detalles Bibliográficos
Autores principales:	Andreev, Dmitry E, O’Connor, Patrick BF, Zhdanov, Alexander V, Dmitriev, Ruslan I, Shatsky, Ivan N, Papkovsky, Dmitri B, Baranov, Pavel V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419486/ https://www.ncbi.nlm.nih.gov/pubmed/25943107 http://dx.doi.org/10.1186/s13059-015-0651-z

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