A procedure for the preparation and isolation of nucleoside-5’-diphosphates

Tris[bis(triphenylphosphoranylidene)ammonium] pyrophosphate (PPN pyrophosphate) was used in the S(N)2 displacements of the tosylate ion from 5’-tosylnucleosides to afford nucleoside-5’-diphosphates. Selective precipitation permitted the direct isolation of nucleoside-5’-diphosphates from crude react...

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Detalles Bibliográficos
Autores principales: Korhonen, Heidi J, Bolt, Hannah L, Hodgson, David R W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419508/
https://www.ncbi.nlm.nih.gov/pubmed/25977720
http://dx.doi.org/10.3762/bjoc.11.52
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author Korhonen, Heidi J
Bolt, Hannah L
Hodgson, David R W
author_facet Korhonen, Heidi J
Bolt, Hannah L
Hodgson, David R W
author_sort Korhonen, Heidi J
collection PubMed
description Tris[bis(triphenylphosphoranylidene)ammonium] pyrophosphate (PPN pyrophosphate) was used in the S(N)2 displacements of the tosylate ion from 5’-tosylnucleosides to afford nucleoside-5’-diphosphates. Selective precipitation permitted the direct isolation of nucleoside-5’-diphosphates from crude reaction mixtures.
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spelling pubmed-44195082015-05-14 A procedure for the preparation and isolation of nucleoside-5’-diphosphates Korhonen, Heidi J Bolt, Hannah L Hodgson, David R W Beilstein J Org Chem Letter Tris[bis(triphenylphosphoranylidene)ammonium] pyrophosphate (PPN pyrophosphate) was used in the S(N)2 displacements of the tosylate ion from 5’-tosylnucleosides to afford nucleoside-5’-diphosphates. Selective precipitation permitted the direct isolation of nucleoside-5’-diphosphates from crude reaction mixtures. Beilstein-Institut 2015-04-10 /pmc/articles/PMC4419508/ /pubmed/25977720 http://dx.doi.org/10.3762/bjoc.11.52 Text en Copyright © 2015, Korhonen et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Letter
Korhonen, Heidi J
Bolt, Hannah L
Hodgson, David R W
A procedure for the preparation and isolation of nucleoside-5’-diphosphates
title A procedure for the preparation and isolation of nucleoside-5’-diphosphates
title_full A procedure for the preparation and isolation of nucleoside-5’-diphosphates
title_fullStr A procedure for the preparation and isolation of nucleoside-5’-diphosphates
title_full_unstemmed A procedure for the preparation and isolation of nucleoside-5’-diphosphates
title_short A procedure for the preparation and isolation of nucleoside-5’-diphosphates
title_sort procedure for the preparation and isolation of nucleoside-5’-diphosphates
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419508/
https://www.ncbi.nlm.nih.gov/pubmed/25977720
http://dx.doi.org/10.3762/bjoc.11.52
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