The preparation of new functionalized [2.2]paracyclophane derivatives with N-containing functional groups

The two isomeric bis(isocyanates) 4,12- and 4,16-di-isocyanato[2.2]paracyclophane, 16 and 28, have been prepared from their corresponding diacids by simple routes. The two isomers are versatile intermediates for the preparation of various cyclophanes bearing substituents with nitrogen-containing fun...

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Autores principales: Hopf, Henning, Narayanan, Swaminathan Vijay, Jones, Peter G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419526/
https://www.ncbi.nlm.nih.gov/pubmed/25977718
http://dx.doi.org/10.3762/bjoc.11.50
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author Hopf, Henning
Narayanan, Swaminathan Vijay
Jones, Peter G
author_facet Hopf, Henning
Narayanan, Swaminathan Vijay
Jones, Peter G
author_sort Hopf, Henning
collection PubMed
description The two isomeric bis(isocyanates) 4,12- and 4,16-di-isocyanato[2.2]paracyclophane, 16 and 28, have been prepared from their corresponding diacids by simple routes. The two isomers are versatile intermediates for the preparation of various cyclophanes bearing substituents with nitrogen-containing functional groups, e.g., the pseudo-ortho diamine 8, the bis secondary amine 23, and the crownophanes 18 and 19. Several of these new cyclophane derivatives (18, 19, 22, 26, 28) have been characterized by X-ray structural analysis.
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spelling pubmed-44195262015-05-14 The preparation of new functionalized [2.2]paracyclophane derivatives with N-containing functional groups Hopf, Henning Narayanan, Swaminathan Vijay Jones, Peter G Beilstein J Org Chem Full Research Paper The two isomeric bis(isocyanates) 4,12- and 4,16-di-isocyanato[2.2]paracyclophane, 16 and 28, have been prepared from their corresponding diacids by simple routes. The two isomers are versatile intermediates for the preparation of various cyclophanes bearing substituents with nitrogen-containing functional groups, e.g., the pseudo-ortho diamine 8, the bis secondary amine 23, and the crownophanes 18 and 19. Several of these new cyclophane derivatives (18, 19, 22, 26, 28) have been characterized by X-ray structural analysis. Beilstein-Institut 2015-04-07 /pmc/articles/PMC4419526/ /pubmed/25977718 http://dx.doi.org/10.3762/bjoc.11.50 Text en Copyright © 2015, Hopf et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Hopf, Henning
Narayanan, Swaminathan Vijay
Jones, Peter G
The preparation of new functionalized [2.2]paracyclophane derivatives with N-containing functional groups
title The preparation of new functionalized [2.2]paracyclophane derivatives with N-containing functional groups
title_full The preparation of new functionalized [2.2]paracyclophane derivatives with N-containing functional groups
title_fullStr The preparation of new functionalized [2.2]paracyclophane derivatives with N-containing functional groups
title_full_unstemmed The preparation of new functionalized [2.2]paracyclophane derivatives with N-containing functional groups
title_short The preparation of new functionalized [2.2]paracyclophane derivatives with N-containing functional groups
title_sort preparation of new functionalized [2.2]paracyclophane derivatives with n-containing functional groups
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419526/
https://www.ncbi.nlm.nih.gov/pubmed/25977718
http://dx.doi.org/10.3762/bjoc.11.50
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