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Mutation Bias, rather than Binding Preference, Underlies the Nucleosome-Associated G+C% Variation in Eukaryotes

The effects of genetic content on epigenetic status have been extensively studied, but how epigenetic status affects genetic content is not well understood. As a key epigenetic factor the nucleosome structure is highly correlated with local G+C% in eukaryotic genomes. The prevailing explanation to t...

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Detalles Bibliográficos
Autores principales: Xing, Ke, He, Xionglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419799/
https://www.ncbi.nlm.nih.gov/pubmed/25786433
http://dx.doi.org/10.1093/gbe/evv053