Recent Positive Selection Has Acted on Genes Encoding Proteins with More Interactions within the Whole Human Interactome

Genes vary in their likelihood to undergo adaptive evolution. The genomic factors that determine adaptability, however, remain poorly understood. Genes function in the context of molecular networks, with some occupying more important positions than others and thus being likely to be under stronger s...

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Detalles Bibliográficos
Autores principales: Luisi, Pierre, Alvarez-Ponce, David, Pybus, Marc, Fares, Mario A., Bertranpetit, Jaume, Laayouni, Hafid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419801/
https://www.ncbi.nlm.nih.gov/pubmed/25840415
http://dx.doi.org/10.1093/gbe/evv055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419801/
https://www.ncbi.nlm.nih.gov/pubmed/25840415
http://dx.doi.org/10.1093/gbe/evv055

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